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What criteria should be used in choosing between additives listed on the label? The two primary factors to consider are how the additives will influence weed control and crop safety. A COC will generally enhance herbicide activity more than a surfactant; however, COC’s often will increase the potential for crop injury. In situations where weeds are under stress or reaching the maximum size specified on the herbicide label, the higher activity of the COC may be necessary to achieve acceptable control.